R&D 2
Result of co-research with Tsukuba University
Study of functions 2nd stage
Study of functions 2nd stage
Apoptosis inductive effect test


Result in Graph Cell Survival Rate & Number


Functionality Study 2nd Stage Result
Result of Multi Caspase Assay Experiement
In long term treatment (10µl/ml ESD 48.72h treatment; 30µl/ml ESD12.48.72hr treatment),
number of apoptosis cell drastically increased.
number of apoptosis cell drastically increased.
No effect of ESD treatment verified in Caco-2 cell survival rate compared to the controlled cell survival rate
In the number of Caco-2 cells, controlled cells increased whilst the increment of
number of cell concentration-dependently became slow under ESD treatment

The suppression effect on human originated ESD colorectal cancer cell
is estimated due to suppression on apoptosis cell and cell division.
is estimated due to suppression on apoptosis cell and cell division.